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Celebration of Research 2011

A Celebration of Research recognizes the Goodenow Lab

Maureen Goodenow, Ph.D., the Stephany W. Holloway University chair for AIDS Research, was presented with the Basic Science Research Award by Stephen Sugrue, Ph.D.

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At the center of our research is the Human Immunodeficiency Virus.

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Nature Immunology

Serine-threonine kinases in TCR signaling

TCR engagement triggers activation of downstream kinases. Navarro and Cantrell discuss how the network of serine/threonine kinases instruct T cell metabolism to participate in immune responses.

Integrative biology of T cell activation

TCR ligation activates multiple downstream pathways that lead to myriad functional outputs. Malissen and colleagues discuss how unbiased mass spectrometry using signaling hub 'bait' molecules, such as...

Insights into the initiation of TCR signaling

How agonist peptides initiate the T cell antigen receptor (TCR) signaling cascade is widely debated. Weiss and Chakraborty discuss current models of the proximal signaling events that ensue upon...