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Celebration of Research 2011

A Celebration of Research recognizes the Goodenow Lab

Maureen Goodenow, Ph.D., the Stephany W. Holloway University chair for AIDS Research, was presented with the Basic Science Research Award by Stephen Sugrue, Ph.D.

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Our Research

At the center of our research is the Human Immunodeficiency Virus.

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Nature Immunology

The balance between protective and pathogenic immune responses in the TB-infected lung

Mycobacterial tuberculosis remains a disease of major importance. In this Focus Review, Orme, Robinson and Cooper discuss lung immune responses to mycobacteria and describe how the bacterium can...

Stop the executioners

Virus-triggered type I interferon induces the lysine methyltransferase Setdb2; this then generates repressive histone marks on the promoters of genes encoding molecules important for antibacterial...

Antiviral B cell and T cell immunity in the lungs

The lungs are the main site of entry for most viral pathogens. In this Focus Review, Chiu and Openshaw discuss adaptive immune responses to lung-tropic viruses and implications for vaccine...

A surprising role for TLR7

Ligation of the Toll-like receptor TLR7 in human CD4+ T cells elicits an anergic state that may contribute to CD4+ T cell hyporesponsiveness after infection with human immunodeficiency virus type 1...